DEFECTIVE BILIRUBIN CONJUGATION IN G-6-PD DEFICIENT NEONATES † 1306
نویسندگان
چکیده
منابع مشابه
Hyperbilirubinemia Following Exchange Transfusion with G-6-PD Deficient Donor Blood
Background: The incidence of glucose-6-phosphate dehydrogenase (G-6-PD) deficiency in Iran is estimated at 10-14.9%. The donor blood in blood banks is not screened routinely for this enzyme deficiency and such blood may be used for neonatal exchange transfusion.Objective: To study the effect of G-6-PD deficient blood in neonatal exchange blood transfusion.Methods: In a prospective study, serum...
متن کاملBilirubin conjugation, reflected by conjugated bilirubin fractions, in glucose-6-phosphate dehydrogenase-deficient neonates: a determining factor in the pathogenesis of hyperbilirubinemia.
BACKGROUND AND OBJECTIVE Glucose-6-phosphate dehydrogenase (G-6-PD) deficiency is frequently associated with neonatal hyperbilirubinemia, which in severe cases may cause kernicterus and death. Because G-6-PD-deficient individuals frequently undergo acute, trigger-induced hemolytic episodes, increased hemolysis has frequently been implied in the pathogenesis of this neonatal hyperbilirubinemia. ...
متن کاملOC-Thalassaemia and hyperbilirubinaemia in G-6-PD-deficient newborns
Gairdner D, Pearson J. A growth chart for premature and other infants. Arch Dis Child 1971; 46: 783-7. 2 Illingworth R S, Lutz W. Head circumference of infants related to body weight. Arch Dis Child 1965; 40: 672-6. 3 Baum J D, Searls D. Head shape and size of newborn infants. Dev Med Child Neurol 1971; 13: 572-5. lllingworth R S. The development of the infant and young child. 5th ed. Edinburgh...
متن کاملBilirubin Conjugation by Human Liver
Adlard, B. P. F., and Lathe, G. H. (1970). Archives of Disease in Childhood, 45, 186. Breast milk jaundice: effect of 3oc,20,B-pregnanediol on bilirubin conjugation by human liver. The effect of 3ot,20fl-pregnanediol and other steroids on bilirubin conjugation was examined using liver tissue from human and four other species. Neither 3Ix,20fl-pregnanediol nor 3a,200c-pregnanediol inhibited conj...
متن کاملEffect of hemolysis and hyperbilirubinemia in glucose-6-phosphate dehydrogenase-deficient neonates
Objective: Recently, the role of hemolysis in the pathophysiology of hyperbilirubinemia in glucose-6phosphate dehydrogenase (G6PD) deficient neonates has been questioned and decreased bilirubin conjugation has been suggested. We conducted a study to evaluate the effect of hemolysis on these neonates at the 17-Shahrivar Children Hospital in Rasht. Methods: In this cross-sectional s...
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ژورنال
عنوان ژورنال: Pediatric Research
سال: 1996
ISSN: 0031-3998,1530-0447
DOI: 10.1203/00006450-199604001-01329